Djokovic defeats gallant Millman to advance

Novak Djokovic Marin Cilic Kei Nishikori Madison Keys are quarterfinal headliners

Instead, it resembled their 2010 second-round match in Flushing Meadows, when Nishikori rallied to win in five sets in 4:59, the fifth-longest men's singles match by time in U.S. Open history.

A gutsy display from the 55th ranked player certainly earned him the adoration of the crowd on Arthur Ashe, but the 30-year old was found wanting at crucial points during the game as the more-experienced Djokovic turned things up a notch whenever needed.

John McEnroe has come under fire for his early treatment of Australia's John Millman in commentary at the US Open.

The No. 20 seed continued what's been a largely dominant run through the draw by winning in just 57 minutes, the third time in her five matches she didn't even have to play an hour.

This proved to be Nishikori's day, though, as he ground out a 6-2 4-6 7-6 (7/5) 4-6 6-4 victory to mark a landmark moment for Japan after Naomi Osaka's win over Lesia Tsurenko earlier.

"I personally have never sweat as much as I have here", he said.

Osaka will face home favorite Madison Keys, who defeated Spain's Carla Suarez Navarro 6-4 6-3 on Wednesday.

Francesca Schiavone, the 2010 French Open victor, held a news conference to announce her retirement as Kei Nishikori and Marin Cilic battled it out in another lengthy contest on Arthur Ashe Stadium.

Tsurenko labored in the heat during her fourth-round victory over Marketa Vondrousova, having her temperature and blood checked during a medical timeout in the first set and almost quitting when she trailed early in the second.

If Djokovic wins in NY, he'll join Pete Sampras on 14 grand slam triumphs, a total only bettered by Roger Federer and Rafael Nadal.

Millman held serve from 0-40 down in the opening game of the second set but at 4-4 he double-faulted on break point.

John Millman had the biggest upset of the U.S. Open two nights ago when he sent No. 2 Roger Federer packing.

"I accomplished that. So I'm very, very happy and lucky that, as we say in Italia, 'It's done, this part is done.' After 20 years of career and life, I have new dreams".

Schiavone said: "I arrived at this decision to say goodbye to tennis with my heart, because my head, when I arrived here, said, "please go to the court, fight, because I can beat many other players".

But after reaching the final in Monte Carlo, the French Open fourth round and the Wimbledon quarter-finals, Nishikori believes an elusive first grand slam is within reach. That all changed in the middle of the second set, when the Croat with the score 4:2 managed to lose four games in a row.

"I forgot about it [beating Djokovic]", said Nishikori.

He said: "He's got one of the best two-handed backhands in the game and very quick". Just put me back a bit on my back foot. He was able to come through on only four of his 20 break points.

Nishikori's relatively week serve could be the deciding factor here, as if Cilic can get into his groove he will look to punish that aspect of his opponent's game, especially the second serve.

Two inexplicable double-faults as the Japanese altered his return positions handed Nishikori the initiative and he produced a sumptuous backhand return victor down the line on set point to deepening Cilic's misery.

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